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  2. Reader Rabbit Toddler - Wikipedia

    en.wikipedia.org/wiki/Reader_Rabbit_Toddler

    The activities in the game are intended to prepare a child for preschool including number and letter recognition and sequencing, patterns, matching, sorting and basic phonic skills. Difficulty in the game increases with every success made, although the focus is not about getting answers correct but rather learning from incorrect ones. [3]

  3. Stratigraphic cycles - Wikipedia

    en.wikipedia.org/wiki/Stratigraphic_Cycles

    Sequence or Synthem 10-100 Third-order Mesothem 1-10 Fourth-order Cyclothem .2-.5 ... Volcanic activity was also high in the greenhouse years. [3]

  4. Third-generation sequencing - Wikipedia

    en.wikipedia.org/wiki/Third-generation_sequencing

    Third-generation sequencing (also known as long-read sequencing) is a class of DNA sequencing methods which produce longer sequence reads, under active development since 2008. [ 1 ] Third generation sequencing technologies have the capability to produce substantially longer reads than second generation sequencing , also known as next-generation ...

  5. DNA sequencer - Wikipedia

    en.wikipedia.org/wiki/DNA_sequencer

    The AB370A was able to sequence 96 samples simultaneously, 500 kilobases per day, and reaching read lengths up to 600 bases. This was the beginning of the "first generation" of DNA sequencers, [2] [3] which implemented Sanger sequencing, fluorescent dideoxy nucleotides and polyacrylamide gel sandwiched between glass plates - slab gels. The next ...

  6. Scaffolding (bioinformatics) - Wikipedia

    en.wikipedia.org/wiki/Scaffolding_(bioinformatics)

    Most high-throughput, next generation sequencing platforms produce shorter read lengths compared to Sanger sequencing.These new platforms are able to generate large quantities of data in short periods of time, but until methods were developed for de novo assembly of large genomes from short read sequences, Sanger sequencing remained the standard method of creating a reference genome. [10]

  7. Sequencing - Wikipedia

    en.wikipedia.org/wiki/Sequencing

    DNA sequencing is the process of determining the nucleotide order of a given DNA fragment. So far, most DNA sequencing has been performed using the chain termination method developed by Frederick Sanger. This technique uses sequence-specific termination of a DNA synthesis reaction using modified nucleotide substrates.