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Ovarian stimulation with the aromatase inhibitor letrozole has been proposed for ovulation induction in order to treat unexplained female infertility. In a multi-center study funded by the National Institute of Child Health and Development, ovarian stimulation with letrozole resulted in a significantly lower frequency of multiple gestation (i.e., twins or triplets) but also a lower frequency ...
Two distinct drug classes in which cardiotoxicity can occur are in anti-cancer and antiarrhythmic drugs. Anti-cancer drug classes that cause cardiotoxicity include anthracyclines, monoclonal antibodies, and antimetabolites. This form generally manifests as a progressive form of heart failure, but can also manifest as an harmful arrhythmia. [2]
Heart palpitations and arrhythmias, hypotension, nausea, vomiting, abdominal pain, respiratory system paralysis, death [4] [5] Aloe vera juice medicinal aloe Aloe vera "abdominal pain, diarrhea, potentially carcinogenic, with others can potentiate cardiac glycosides and antiarrhythmic agents" [3] Anthranoid laxatives
These treatments can include selective estrogen receptor modulators like clomiphene , a derivative of clomiphene called enclomiphene, or aromatase inhibitors like anastrozole (Arimidex®). These ...
Biological Toxins such as Diphtheria toxin [18]; Radiation Therapy is known to cause radiation-induced heart disease (RIHD) [19] These agents can lead to varying degrees of cardiotoxicity, and their effects may be dose-dependent and influenced by individual factors such as pre-existing cardiovascular disease and genetic predispositions that can foster greater sensitivity to any cardiac damage.
DHEA can also interfere with some medications, including: Fulvestrant. Antidepressants. Medications changed by the liver. Aromatase inhibitors. Anticoagulant and antiplatelet drugs. Tamoxifen ...
Unlike a sudden cardiac event—say, a heart attack—valvular disease develops slowly, over five to 10 years. Many patients don’t experience symptoms until later in the course of disease, if at ...
The medication has been found to achieve 96.7% to 97.3% inhibition of aromatase at a dosage of 1 mg/day and 98.1% inhibition of aromatase at a dosage of 10 mg/day in humans. [3] [2] As such, 1 mg/day is considered to be the minimal dosage required to achieve maximal suppression of aromatase with anastrozole. [3]
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