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Hershey and Chase concluded that DNA, not protein, was the genetic material. They determined that a protective protein coat was formed around the bacteriophage, but that the internal DNA is what conferred its ability to produce progeny inside a bacterium. They showed that, in growth, protein has no function, while DNA has some function.
In 1952, Hershey and Chase [19] provided key evidence that the phage DNA, as distinct from protein, enters the host bacterial cell upon infection and is thus the genetic material of the phage. This finding suggested that DNA is, in general, the genetic material of different organisms.
Experiments conducted in 1952 by Alfred Hershey and Martha Chase demonstrated how the DNA of viruses is injected into the bacterial cells, while most of the viral proteins remain outside. [1] [2] The injected DNA molecules cause the bacterial cells to produce more viral DNA and proteins. These discoveries supported that DNA, rather than ...
In 1971, he edited The Bacteriophage λ, an extensive volume on the subject, published by CSHL Press that same year. [1] In 1981, Hershey became a founding member of the World Cultural Council. [9] Hershey died from congestive heart failure on May 22, 1997 at his home in Laurel Hollow, New York. [10] He was 88 years old.
The Hershey–Chase experiments were conducted by Alfred Hershey and Martha Chase in 1952 using the T2 bacteriophage (pictured), which is composed of DNA wrapped in a protein shell. Hershey and Chase labelled either the phage DNA using radioactive phosphorus-32 or the protein using radioactive sulphur-35.
After the discovery of the structure of DNA in 1953, it was still unclear how DNA replicated. The favored model at the time was semi-conservative replication, but experimental proof was needed. The Meselson–Stahl experiment , [ 13 ] performed by Matthew Meselson and Franklin Stahl in 1958, was the key experiment that provided convincing ...
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A bacteriophage is a type of virus that infects bacteria. Bacteriophage are likely the most numerous "organisms" on Earth [1] [2] The main article for this category is Bacteriophage .