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The insular cortex is divided by the central sulcus of the insula, into two parts: the anterior insula and the posterior insula in which more than a dozen field areas have been identified. The cortical area overlying the insula toward the lateral surface of the brain is the operculum (meaning lid). The opercula are formed from parts of the ...
Meta-analyses of structural MRI studies have shown that certain brain regions (e.g., the left rostral anterior cingulate cortex, fronto-insular cortex, ventral prefrontal cortex, and claustrum) are smaller in people with bipolar disorder, whereas other regions are larger (lateral ventricles, globus pallidus, subgenual anterior cingulate, and ...
This region is extremely rich in serotonin transporters and is considered as a governor for a vast network involving areas like hypothalamus and brain stem, which influences changes in appetite and sleep; the amygdala and insula, which affect the mood and anxiety; the hippocampus, which plays an important role in memory formation; and some parts of the frontal cortex responsible for self ...
The right insular cortex probably plays the most significant role in these phenomena. Similar lateralization is probably involved in cardiovascular malfunction in patients with head injury, stroke, multiple sclerosis, brain tumors, meningitis and encephalitis, migraine, cluster headache and neurosurgical procedures.
A 2016 meta analysis reported that bipolar disorder was associated with grey matter reductions bilaterally in the ACC, vmPFC, and insula extending to the temporal lobe. When compared with grey matter reductions in unipolar depression, significant overlap occurred in the insular and medial prefrontal regions.
Acupuncture is an alternative treatment type for many people with anxiety and depression. Typically, it is self-prescribed by patients; [93] however, results are inconclusive on its ability to manage symptoms of depression. [94] Recently, Massage therapy has been shown to have the ability to reduce symptoms of generalized anxiety disorder. [95]
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