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The term lymphadenopathy strictly speaking refers to disease of the lymph nodes, [1] though it is often used to describe the enlargement of the lymph nodes. Similarly, the term lymphadenitis refers to inflammation of a lymph node, but often it is used as a synonym of lymphadenopathy. Cervical lymphadenopathy is a sign or a symptom, not a diagnosis.
About 95% of the scrofula cases in adults are caused by Mycobacterium tuberculosis, most often in immunocompromised patients (about 50% of cervical tuberculous lymphadenopathy). In immunocompetent children, scrofula is often caused by atypical mycobacteria ( Mycobacterium scrofulaceum ) and other nontuberculous mycobacteria (NTM).
The signs and symptoms of Kikuchi disease are fever, enlargement of the lymph nodes (lymphadenopathy), skin rashes, and headache. [7] In sixty to ninety percent of cases, lymphadenopathy presents in the posterior cervical lymph nodes with diameter enlargement typically being between one and two centimeters, but up to seven centimeters has been reported in literature.
Cervical adenitis is an inflammation of a lymph node in the neck. Tuberculous adenitis ( scrofula ) is a tuberculous infection of the skin of the neck caused by Mycobacterium tuberculosis . Non-tuberculous adenitis can also be caused by Mycobacterium scrofulaceum or Mycobacterium avium .
In children, rubella normally causes symptoms that last two days and include: Rash begins on the face which spreads to the rest of the body. Low fever of less than 38.3 °C (100.9 °F). Posterior cervical lymphadenopathy. [14] In older children and adults, additional symptoms may be present, including [citation needed] Swollen glands
It occurs primarily in elderly adults, far less frequency in younger adults, and rarely in children. Elderly adults present with B symptoms (i.e. fever, night sweats, and weight loss), swollen lymph nodes, and symptoms due to malignant cell infiltrations into the upper gastrointestinal tract, lungs, upper airways, and/or other organs. Younger ...
Children often have generalized lymphadenopathy of the head and neck, or even PGL, without the finding of a sinister cause. At puberty this usually disappears. The immune system of some people may be sensitized by exposure to a living exogenous irritant such as a bacterial or viral infection , which then results in PGL after the organism has ...
Peripheral lymphadenopathy is very common, particularly involving the cervical (the most common head and neck manifestation of the disease), axillary, epitrochlear, and inguinal nodes. [71] Approximately 75% of cases show microscopic involvement of the spleen, although only in about 5–10% of cases does splenomegaly appear.