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An infantile hemangioma (IH), sometimes called a strawberry mark due to appearance, is a type of benign vascular tumor or anomaly that affects babies. [1] [2] Other names include capillary hemangioma, [6] "strawberry hemangioma", [7]: 593 strawberry birthmark [8] and strawberry nevus. [6] and formerly known as a cavernous hemangioma.
A hemangioma or haemangioma is a usually benign vascular tumor derived from blood vessel cell types. The most common form, seen in infants, is an infantile hemangioma , known colloquially as a "strawberry mark", most commonly presenting on the skin at birth or in the first weeks of life.
Second to the liver, the brain is the most common place for diffuse neonatal hemangiomatosis. With that being said, there have only been only 16 cases of cranial hemangioma. Nine out of the total 16 cases undergo neurological manifestations. With damage to the brain, the skin red discolorations are usually 0.5–1.5 centimeters.
The majority of diagnoses of CCM are in adults; however, 25% of cases of CCM are children. [6] Approximately 5% of adults have liver hemangiomas in the United States, but most are asymptomatic. [30] Liver hemangiomas usually occur between the ages of 30 and 50 and more commonly in women. [4] Cases of infantile liver cavernomas are extremely rare.
A cavernous liver hemangioma or hepatic hemangioma is a benign tumor of the liver composed of large vascular spaces lined by monolayer hepatic endothelial cells. It is the most common benign liver tumour, and is usually asymptomatic and diagnosed incidentally on radiological imaging or during laparotomy for other intra-abdominal issues.
Cavernous hemangiomas (also called hepatic hemangioma or liver hemangioma) are the most common type of benign liver tumor, found in 3%– 10% of people. [2] They are made up of blood clusters that are surrounded by endothelial cells. [5] These hemangiomas get their blood supply from the hepatic artery and its branches. [5]
Kasabach–Merritt syndrome (KMS), also known as hemangioma with thrombocytopenia, [1] is a rare disease, usually of infants, in which a vascular tumor leads to decreased platelet counts and sometimes other bleeding problems, [2] which can be life-threatening. [3] It is also known as hemangioma thrombocytopenia syndrome.
Like juvenile hemangiomas, infantile hemangiopericytomas only appear in the subcutis and affect newborns throughout their first year of life. They are characterized by being multilobulated and frequently having separate perivascular and intravascular satellite nodules outside of the main tumor mass. [2]