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Figure. 1: Cable theory's simplified view of a neuronal fiber. In neuroscience, classical cable theory uses mathematical models to calculate the electric current (and accompanying voltage) along passive [a] neurites, particularly the dendrites that receive synaptic inputs at different sites and times.
Saltatory conduction. In neuroscience, nerve conduction velocity (CV) is the speed at which an electrochemical impulse propagates down a neural pathway.Conduction velocities are affected by a wide array of factors, which include age, sex, and various medical conditions.
As with most neuronal models, increasing the injected current will increase the firing rate of the neuron. One consequence of the Hopf bifurcation is that there is a minimum firing rate. This means that either the neuron is not firing at all (corresponding to zero frequency), or firing at the minimum firing rate.
A neuron is represented by an RC circuit with a threshold. Each input pulse (e.g. caused by a spike from a different neuron) causes a short current pulse. Voltage decays exponentially. If the threshold is reached an output spike is generated and the voltage is reset. where V m is the voltage across the cell membrane and R m is the membrane ...
At the time of Henneman’s initial study of motor neuron recruitment, [1] it was known that neurons varied greatly in size, that is in the diameter and extent of the dendritic arbor, size of the soma, and diameter of axon. However, the functional significance of neuron size was not yet known.
These characteristics are also known as I–V curves, referring to the standard symbols for current and voltage. In electronic components with more than two terminals, such as vacuum tubes and transistors, the current–voltage relationship at one pair of terminals may depend on the current or voltage on a third terminal. This is usually ...
Additionally, the motor unit action potential is an all-or-none phenomenon - once the recruitment threshold (the stimulus intensity at which a motor unit begins to fire) is reached, it fires fully. Electrical stimulation of nerves reverses the recruitment order, due to the lower resistance of the larger motor neuron axons.
As an example, the cardiac action potential illustrates how differently shaped action potentials can be generated on membranes with voltage-sensitive calcium channels and different types of sodium/potassium channels. The second type of mathematical model is a simplification of the first type; the goal is not to reproduce the experimental data ...