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Currently, Kawasaki disease is the most commonly diagnosed pediatric vasculitis in the world. By far, the highest incidence of Kawasaki disease occurs in Japan, with the most recent study placing the attack rate at 218.6 per 100,000 children less than five years of age (about one in 450 children).
Kawasaki disease is a type of vasculitis where the endothelial cells in the coronary arteries become damaged, potentially leading to complications like myocardial infarction and aneurysms. This video covers the known pathophysiology, important signs and symptoms, diagnostic criteria, and treatment.
Kawasaki disease is most commonly seen in infants and children under five years old and is more likely to affect boys. The disease is self-limited which means that the inflammation will resolve after 6 to 8 weeks but if we left it untreated, there is a 20-25% risk of the heart complications we went over. Alright so let’s look at the symptoms ...
The disease spectrum varies from failure of multiple organs to involvement of a single organ. Almost any organ could be impacted; however, polyarteritis nodosa rarely affects the lungs for unknown reasons. [10] Kawasaki disease (KD) is a type of systemic vasculitis of medium-sized vessels with an acute onset that primarily affects young children.
Acquired causes include atherosclerosis in adults, [4] Kawasaki disease in children [5] and coronary catheterization. With the invention of drug eluting stents, there has been more cases implying stents lead to coronary aneurysms. The pathophysiology, although not completely understood, might be comparable to that of aneurysms of larger vessels.
In 2013, Chalke revealed that Charlie had been diagnosed with Kawasaki disease, which is a rare condition that causes inflammation in the blood vessels and mainly impacts children ages 5 and ...
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Kawasaki disease: Fever, conjunctivitis, exanthema, palmoplantar erythema, cervical lymphadenopathy, and mucosal enanthema. [12] [13] Primary small vessel antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis [8] Microscopic polyangiitis