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In the 1920s, Kyusaku Ogino, a Japanese gynecologist, and Hermann Knaus, from Austria, working independently, each made the discovery that ovulation occurs about fourteen days before the next menstrual period. [13] Ogino used his discovery to develop a formula for use in aiding infertile women to time intercourse to achieve pregnancy.
The rule estimates the expected date of delivery (EDD) by adding a year, subtracting three months, and adding seven days to the origin of gestational age. [13] [14] The result is approximately 280 days (40 weeks) from the start of the last menstrual period. Another method is by adding 9 months and 7 days to the first day of the last menstrual ...
Ovulation is an important part of the menstrual cycle in female vertebrates where the egg cells are released from the ovaries as part of the ovarian cycle. In female humans ovulation typically occurs near the midpoint in the menstrual cycle and after the follicular phase. Ovulation is stimulated by an increase in luteinizing hormone (LH).
Post-ovulation methods (i.e., abstaining from intercourse from menstruation until after ovulation) have a method failure rate of 1% per year. The symptothermal method has a method failure rate of 2% per year. Cervical mucus–only methods have a method failure rate of 3% per year. Calendar rhythm has a method failure rate of 9% per year.
The average age of a girl's first period is 12 to 13 (12.5 years in the United States, [6] 12.72 in Canada, [7] 12.9 in the UK [8]) but, in postmenarchal girls, about 80% of the cycles are anovulatory in the first year after menarche, which declines to 50% in the third year, and to 10% by the sixth. [9]
In a reference group representing all women, the 95% prediction interval of the LMP-to-ovulation is 8.2 to 20.5 days. [31] The average time to birth has been estimated to be 268 days (38 weeks and two days) from ovulation, with a standard deviation of 10 days or coefficient of variation of 3.7%. [33]