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The Purification Rundown, also known as the Purif [1] or the Hubbard Method, [2] is a pseudoscientific procedure that advocates of Scientology claim is a detoxification program. There is no evidence for its efficacy in detoxification, and significant evidence from clinicians that it is dangerous.
Prescription niacin preparations in combination with statin drugs (discontinued) are described above. A combination of niacin and laropiprant had been approved for use in Europe and marketed as Tredaptive. Laropiprant is a prostaglandin D2 binding drug shown to reduce niacin-induced vasodilation and flushing side effects.
The detoxification program has been offered for free to rescue workers, and also offered to other New York City residents, some of whom paid $5,000. [ 2 ] [ 22 ] According to tax filings, the project pays some of its money to two bodies that promote the Purification Rundown , both related to the Church of Scientology .
Merck's original idea seemed low risk. Niacin works pretty well at raising good cholesterol but has this annoying side effect of causing patients to feel hot and sweaty (flush). If you can add ...
Even though all mycobacteria produce niacin, M. tuberculosis accumulates an excess of niacin because of its inability to process niacin, excreting the excess niacin into the culture media, thus allowing it to be detected using the niacin test. [3] The niacin test is typically only conducted on slow-growing, granular, tan colored colonies, as ...
Drug detoxification (informally, detox) is variously construed or interpreted as a type of "medical" intervention or technique in regards to a physical dependence mediated by a drug; as well as the process and experience of a withdrawal syndrome or any of the treatments for acute drug overdose (toxidrome).