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Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug. The effects of ototoxicity can be reversible and temporary, or irreversible and permanent. It has been recognized since the 19th century. [1]
Side effects from using ear drops used to remove ear wax are uncommon, but may result in discomfort, irritation, or pain. [5] Antibiotic ear drops may cause ear discomfort, pain, or itching. [1] When cold ear drops are used, it may cause brief but severe dizziness and/or vertigo. [6]
Likewise, combining injected tobramycin with other nephrotoxic or ototoxic drugs can lead to more adverse effects; examples include amphotericin B, ciclosporin, cisplatin, vancomycin, and the diuretic furosemide. Other diuretics can also increase the risk for side effects because they raise tobramycin concentrations in the body fluids. [8]
Tobramycin/dexamethasone, sold under the brand name Tobradex, is a fixed-dose combination medication in the form of eye drops and eye ointment, marketed by Alcon. [1] [2] [3] The active ingredients are tobramycin (an antibiotic) and dexamethasone (a corticosteroid). [2] It is prescribed for the treatment of pink eye in combination with ...
A Connecticut man and woman are accused of manslaughter in connection with the death of a 24-year-old man who was hit by a car in July. Kevin Gangell died after being struck by a vehicle outside ...
“Mom Wives” star Natalie DiDonato has been found after being reported missing. Her mother confirmed to NBC News she is "OK."
A California woman was arrested Wednesday after 27 dead horses were found across her multiple properties, officials said. Jan Johnson, of Clements, was booked in the San Joaquin County Jail on ...
It is a combination of loteprednol, as the etabonate, a corticosteroid; and tobramycin, an aminoglycoside antibiotic. [1] It is used as drops in the eye. [1]