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A medical professional administering nose drops Instillation of eye drops. A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes including creams, foams, gels, lotions, and ointments. [1]
Topical drug delivery (TDD) is a route of drug administration that allows the topical formulation to be delivered across the skin upon application, hence producing a localized effect to treat skin disorders like eczema. [1] [2] The formulation of topical drugs can be classified into corticosteroids, antibiotics, antiseptics, and anti-fungal.
An advantage of a transdermal drug delivery route over other types of medication delivery (such as oral, topical, intravenous, or intramuscular) is that the patch provides a controlled release of the medication into the patient, usually through either a porous membrane covering a reservoir of medication or through body heat melting thin layers ...
The definition of the topical route of administration sometimes states that both the application location and the pharmacodynamic effect thereof is local. [ 3 ] In other cases, topical is defined as applied to a localized area of the body or to the surface of a body part regardless of the location of the effect.
A Medication Administration Record [1] (MAR, or eMAR for electronic versions), commonly referred to as a drug chart, is the report that serves as a legal record of the drugs administered to a patient at a facility by a health care professional. The MAR is a part of a patient's permanent record on their medical chart. The health care ...
Topical delivery is often used for drugs that are easily degraded in the GI tract, or are highly susceptible to hepatic first pass effect. [ 1 ] [ 2 ] Even if the drug has to be administered for long periods of time or can induce adverse drug reactions in parts of the body other than the target location, it can still be formulated as a topical gel.
Buccal administration is a topical route of administration by which drugs held or applied in the buccal (/ ˈ b ʌ k əl /) area (in the cheek) diffuse through the oral mucosa (tissues which line the mouth) and enter directly into the bloodstream.
Figure 5.0 - Example of zero-order release kinetics (y = % of drug released from contact lens; x = time (days)) The drug release rate is extremely important in treating many diseased states of the eye, bacterial infections being one of them. Ciprofloxacin and norfloxacin are drugs that are normally used to treat bacterial infections of the eye.