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The 1999 study mentioned earlier found that DHEA didn’t increase testosterone levels in participants when they took 50 milligrams of DHEA daily for six months. And the pooled analysis found that ...
Dehydroepiandrosterone (DHEA), DHEA sulfate (DHEA-S), and androstenedione may all be considered proandrogens of testosterone. [ 1 ] In the last two decades, prohormones have also been used by bodybuilders, athletes, and nonmedical users of AAS and other hormones to refer to substances that are expected to convert to active hormones in the body.
He also said men with low testosterone “taking DHEA 25-75 mg per day may help. However, it must be done under supervision of a doctor to make sure there is no prostate cancer.”
Levels of DHEA-S in circulation are approximately 250 to 300 times those of DHEA. [20] DHEA-S in turn can be converted back into DHEA in peripheral tissues via steroid sulfatase (STS). [54] [55] The terminal half-life of DHEA is short at only 15 to 30 minutes. [56] In contrast, the terminal half-life of DHEA-S is far longer, at 7 to 10 hours. [56]
Although DHEA-S itself is hormonally inert, it has been thought that it can be converted back into DHEA, [9] which is weakly androgenic and estrogenic, and that DHEA in turn can be transformed into more potent androgens like testosterone and dihydrotestosterone (DHT) as well as estrogens like estradiol.
The Top 12 Foods that Boost Testosterone. This article was reviewed by Martin Miner, MD. As a man, maintaining normal levels of testosterone is critical not just for your health, but also for your ...
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