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  2. Fenofibrate/pravastatin - Wikipedia

    en.wikipedia.org/wiki/Fenofibrate/pravastatin

    The most common side effects are abdominal distension (bloating), abdominal pain (stomach ache), constipation, diarrhea, dry mouth, dyspepsia (heartburn), eructation (belching), flatulence (gas), nausea (feeling sick), abdominal discomfort, vomiting and raised blood levels of liver enzymes.

  3. Cholestasis - Wikipedia

    en.wikipedia.org/wiki/Cholestasis

    Side effects of this treatment are limited and include constipation and bloating. Other commonly used treatments include rifampin , naloxone , and sertraline . In cholestatic liver disease, when bilirubin concentration starts to build up, a deficiency of fat soluble vitamins may also occur. [ 118 ]

  4. Postcholecystectomy syndrome - Wikipedia

    en.wikipedia.org/wiki/Postcholecystectomy_syndrome

    Thus, it may be insufficient for the digestion of fatty foods. Postcholecystectomy syndrome treatment depends on the identified violations that led to it. Typically, the patient is recommended a dietary restriction table with fatty foods, enzyme preparations, antispasmodics, and sometimes cholagogue. [citation needed]

  5. Primary biliary cholangitis - Wikipedia

    en.wikipedia.org/wiki/Primary_biliary_cholangitis

    Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver. [1] [2] [3] It results from a slow, progressive destruction of the small bile ducts of the liver, causing bile and other toxins to build up in the liver, a condition called cholestasis.

  6. Fatty liver disease - Wikipedia

    en.wikipedia.org/wiki/Fatty_liver_disease

    Fatty liver disease (FLD), also known as hepatic steatosis and steatotic liver disease (SLD), is a condition where excess fat builds up in the liver. [1] Often there are no or few symptoms. [1] [2] Occasionally there may be tiredness or pain in the upper right side of the abdomen. [1] Complications may include cirrhosis, liver cancer, and ...

  7. Gastrointestinal disease - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_disease

    Chronic liver disease may result in a buildup of fluid in the abdomen, yellowing of the skin or eyes, easy bruising, immunosuppression, and feminization. [11] Portal hypertension is often present, and this may lead to the development of prominent veins in many parts of the body, such as oesophageal varices , and haemorrhoids .

  8. First pass effect - Wikipedia

    en.wikipedia.org/wiki/First_pass_effect

    First-pass metabolism may occur in the liver (for propranolol, lidocaine, clomethiazole, and nitroglycerin) or in the gut (for benzylpenicillin and insulin). [4] The four primary systems that affect the first pass effect of a drug are the enzymes of the gastrointestinal lumen, [5] gastrointestinal wall enzymes, [6] [7] [8] bacterial enzymes [5] and hepatic enzymes.

  9. Autoimmune hepatitis - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_hepatitis

    The choice for medical treatment should be based on the individual's severity of symptoms, quantitative elevation of liver enzymes and antibody levels, findings on liver biopsy, and ability to tolerate side effects of medical therapy. [citation needed]