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Bag and contents of a well-known early brand of synthetic cannabinoids named Spice that contains herbs covered with synthetic cannabinoids, now illegal throughout much of the world. Synthetic cannabinoids are a class of designer drug molecules that bind to the same receptors to which cannabinoids (THC, CBD and many others) in cannabis plants ...
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Compared with classical cannabinoids, synthetic cannabinoids differ structurally. Some common synthetic cannabinoids are available in the market such as JWH-018, which is the most well-known naphthoylindole and JWH-250, a phenylacetylindole. They are sold under the brand name ”Spice” as a recreational drug over the past decade. [4]
APICA (2NE1, SDB-001, N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide) is an indole based drug that acts as a potent agonist for the cannabinoid receptors. [1]It had never previously been reported in the scientific or patent literature, and was first identified by laboratories in Japan in March 2012 as an ingredient in synthetic cannabis smoking blends, along with its indazole derivative ...
JWH-073, a synthetic cannabinoid, is an analgesic chemical from the naphthoylindole family that acts as a full agonist [3] at both the CB 1 and CB 2 cannabinoid receptors. It is somewhat selective for the CB 1 subtype, with affinity at this subtype approximately 5× the affinity at CB 2. [4]
ADB-CHMINACA (also known as ADMB-CHMINACA [3] and MAB-CHMINACA) is an indazole-based synthetic cannabinoid. It is a potent agonist of the CB 1 receptor with a binding affinity of K i = 0.289 nM and was originally developed by Pfizer in 2009 as an analgesic medication. [4] [5] It was identified in cannabinoid blends in Japan in early 2015. [6]
Marketed under the names spice, spike, flamingo, or K2 — this underground drug has become one of the most inexpensive and dangerous ways to get high, reports say. Videos surfacing online have ...
'MDMB-CHMICAa' [3] is an indole-based synthetic cannabinoid that is a potent agonist of the CB 1 receptor and has been sold online as a designer drug. [ 2 ] [ 4 ] [ 5 ] [ 6 ] While MDMB-CHMICA was initially sold under the name "MMB-CHMINACA", the compound corresponding to this code name (i.e. the isopropyl instead of t-butyl analogue of MDMB ...