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The major causes of sporadic breast cancer are associated with hormone levels. Breast cancer is promoted by estrogen. This hormone activates the development of breast throughout puberty, menstrual cycles and pregnancy. The imbalance between estrogen and progesterone during the menstrual phases causes cell proliferation.
If these effects found in rodents carry over to humans, even minimal exposure to BPA could cause an increased risk for breast cancer. [81] The elevated incidence of breast cancer in women has been associated with prolonged exposure to high levels of estrogens. Xenoestrogens such as BPA have the capacity to perturb normal hormonal actions.
ERα and ERβ also mediate Selective estrogen-receptor modulators' (SERMs') function, [17] but the selective ERα agitator can always cause some side effects such as breast cancer or endometrial hyperplasia, while the selective ERβ agitator may play an active effect on such diseases. So, the selective ERβ agitator has more clinical value for ...
About 80% of breast cancers feed off estrogen; therefore, suppression of this hormone is routinely recommended for treatment. The associated symptoms that come with losing the hormone are accepted ...
Initially, I was wary about using an estrogen product because my breast cancer was hormone sensitive, but he reaffirmed that the research regarding topical estrogen and breast cancer risk shows ...
Estradiol has been tied to the development and progression of cancers such as breast cancer, ovarian cancer and endometrial cancer. Estradiol affects target tissues mainly by interacting with two nuclear receptors called estrogen receptor α (ERα) and estrogen receptor β (ERβ).
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