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Hippocampus in the human brain Nissl-stained coronal section of the brain of a macaque monkey, showing hippocampal formation and subfields (circled). Hippocampus anatomy describes the physical aspects and properties of the hippocampus, a neural structure in the medial temporal lobe of each cerebral hemisphere of the brain.
Its various components support a variety of functions including emotion, behavior, long-term memory, and olfaction. [2] The limbic system is involved in lower order emotional processing of input from sensory systems and consists of the amygdala, mammillary bodies, stria medullaris, central gray and dorsal and ventral nuclei of Gudden. [3]
The dentate gyrus (DG) is one of the subfields of the hippocampus, in the hippocampal formation.The hippocampal formation is located in the temporal lobe of the brain, and includes the hippocampus (including CA1 to CA4) subfields, and other subfields including the dentate gyrus, subiculum, and presubiculum.
In 1937, Papez theorized that a neural circuit (the Papez circuit) including the hippocampal formation and the cingulate gyrus constitutes the neural substrate of emotional behavior, [3] and Klüver and Bucy reported that, in monkeys, resection involving the hippocampal formation and the amygdaloid complex has a profound effect on emotional ...
The hippocampal subfields are four subfields CA1, CA2, CA3, and CA4 that make up the structure of the hippocampus. Regions described in the hippocampus are the head, body, and tail, and other hippocampal subfields include the dentate gyrus , the presubiculum , and the subiculum .
The hippocampus also encodes emotional context from the amygdala. This is partly why returning to a location where an emotional event occurred may evoke that emotion. There is a deep emotional connection between episodic memories and places. [69] Due to bilateral symmetry the brain has a hippocampus in each cerebral hemisphere.
Coronal section of brain. Cingulate cortex is shown in yellow. The cingulate cortex is a part of the brain situated in the medial aspect of the cerebral cortex. The cingulate cortex includes the entire cingulate gyrus, which lies immediately above the corpus callosum, and the continuation of this in the cingulate sulcus.
The circuit connects the hypothalamus and the cortex and acts as the emotional system of the brain. "The cingulate cortex projects to the hippocampus, and the hippocampus projects to the hypothalamus by way of the bundle of axons called the fornix. Hypothalamic effects reach the cortex via a relay in the anterior thalamic nuclei." [7]