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The serum-ascites albumin gradient or gap (SAAG) is a calculation used in medicine to help determine the cause of ascites. [1] The SAAG may be a better discriminant than the older method of classifying ascites fluid as a transudate versus exudate. [2] The formula is as follows: SAAG = (serum albumin) − (albumin level of ascitic fluid).
In alcoholic liver disease, the mean ratio is 1.45, and mean ratio is 1.33 in post necrotic liver cirrhosis. Ratio is greater than 1.17 in viral cirrhosis, greater than 2.0 in alcoholic hepatitis, and 0.9 in non-alcoholic hepatitis. Ratio is greater than 4.5 in Wilson disease or hyperthyroidism. [6]
The INR is a corrected ratio of a patient's PT to normal Activated partial thromboplastin time (APTT) 18, [15] 30 [5] [18] 28, [15] 42, [5] 45 [18] s: Thrombin clotting time (TCT) 11: 18: s: Fibrinogen: 1.7, [15] 2.0 [5] 3.6, [5] 4.2 [15] g/L: Antithrombin: 0.80 [5] 1.2 [5] kIU/L: 0.15, [151] 0.17 [152] 0.2, [151] 0.39 [152] mg/mL Bleeding time ...
The proportion of AST to ALT in hepatocytes is about 2.5:1, but because AST is removed from serum by the liver sinusoidal cells twice as quickly (serum half-life t 1/2 = 18 hr) compared to ALT (t 1/2 = 36 hr), so the resulting serum levels of AST and ALT are about equal in healthy individuals, resulting in a normal AST/ALT ratio around 1.
1401 12944 Ensembl ENSG00000132693 ENSMUSG00000037942 UniProt P02741 P14847 RefSeq (mRNA) NM_000567 NM_001329057 NM_001329058 NM_001382703 NM_007768 RefSeq (protein) NP_000558 NP_001315986 NP_001315987 NP_001369632 NP_031794 Location (UCSC) Chr 1: 159.71 – 159.71 Mb Chr 1: 172.53 – 172.66 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse C-reactive protein (CRP) is an annular (ring ...
It is an alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6–1.2 mg/mL (1–3% plasma protein). [2] Plasma levels are affected by pregnancy, burns, certain drugs, and certain diseases, particularly HIV. [2]
Thyroid function tests (TFTs) is a collective term for blood tests used to check the function of the thyroid. [1] TFTs may be requested if a patient is thought to suffer from hyperthyroidism (overactive thyroid) or hypothyroidism (underactive thyroid), or to monitor the effectiveness of either thyroid-suppression or hormone replacement therapy.
97.0–99.5% (to SHBG Tooltip sex hormone-binding globulin and albumin) [1] Metabolism: Liver (mainly reduction and conjugation) Elimination half-life: