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Indometacin, also known as indomethacin, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling from inflammation. It works by inhibiting the production of prostaglandins , endogenous signaling molecules known to cause these symptoms.
NSAIDs are often used in treatment of acute gout attacks. COX-2 inhibitors appear to work as well as nonselective NSAIDs, such as aspirin. [9] They have not been compared to other treatment options such as colchicine or glucocorticoids. [9] [10]
Periods when gout symptoms are more severe are called gout flares or gout attacks. A gout flare comes on suddenly, and symptoms are often intense. This will most commonly happen at night.
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Gout often affects the knee or big toe, but can attack any joint. (Getty Images) (perfectlab via Getty Images) ... “Gout is genetic and can run in families,” says Iroku-Malize.
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