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The small number of available trials do not support the use of statins as an adjunctive therapy or as a monotherapy in multiple sclerosis. [223] A modelling study in the UK funded by the NIHR found that people aged 70 and older who take statins live longer in good health than those who do not, regardless of whether they have cardiovascular disease.
The findings show a decrease in mortality among people 60 years of age and older — including people over the age of 85 — who took statins. The study is published in Annals of Internal Medicine .
A new way of determining heart disease risk may result in millions fewer people getting prescriptions for statins, according to new research. Heart doctors warned, however, that more information ...
Even in the oldest group, age 85 and older, statin use was linked to a lower incidence of heart disease and all-cause mortality. Additionally, statins did not appear to increase the risk of ...
[2] [7] Of the 4,444 people enrolled in the study, 3,617 were men and 827 women, [5] 2,223 were randomly assigned a placebo and 2,221 were given 20 to 40 mg of simvastatin daily. [1] The plan was to follow the participants for a minimum of three years or until such a time as total mortality reached 440 deaths.
[5] [6] [7] The study's authors estimated that the number needed to treat with rosuvastatin to prevent one cardiovascular event was 95 over two years, extrapolated to 25 over five years. The trial was stopped early, after just 1.9 years median duration, by the study's Independent Data Monitoring Board, because the interim results met the study ...