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Positive chemotaxis occurs if the movement is toward a higher concentration of the chemical in question; negative chemotaxis if the movement is in the opposite direction. Chemically prompted kinesis (randomly directed or nondirectional) can be called chemokinesis.
CXCL10 is secreted by several cell types in response to IFN-γ.These cell types include monocytes, endothelial cells and fibroblasts. [5] CXCL10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and ...
Chemotaxis assays are experimental tools for evaluation of chemotactic ability of prokaryotic or eukaryotic cells. A wide variety of techniques have been developed. A wide variety of techniques have been developed.
Chemotaxis also plays an essential role in several diseases, such as tumor metastasis, the recruitment of T-lymphocytes during inflammation, and HIV-1 entry into T cells. [6] [9] [10] At the core of chemotaxis are specialized sensory cells called chemoreceptors. These cells allow an organism to detect chemical molecules within its environment ...
Of the two directional varieties of chemotaxis, chemoattraction has been studied to a much greater extent. Only recently have the key components of the chemorepulsive pathway been elucidated. [ 1 ] The exact mechanism is still being investigated, and its constituents are currently being explored as likely candidates for immunotherapies.
The International Classification of Diseases for Oncology (ICD-O) is a domain-specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries. It is currently in its third revision (ICD-O-3). ICD-10 includes a list of ...
The movement is characteristically directional. The movement may be positive or negative. A positive taxis is one in which the organism or a cell gravitates towards the source of stimulation (attraction). A negative taxis is when the organism or a cell moves away from the source of stimulation (repulsion).
A chemical gradient can influence the growth of the organism in a positive or negative way. Positive growth is characterized by growing towards a stimulus and negative growth is growing away from the stimulus. [2] Chemotropism is slightly different from Chemotaxis, the major difference being that chemotropism is related to growth, while ...