Ads
related to: autoimmune gfap- View Patient Stories
Watch Videos of Patient Stories
Today to Start Your T1D Journey.
- See the FAQs
Get the Answers to Frequently
Asked Questions Today.
- Join the Support Program
View Resources & Copay Assistance.
Terms & Conditions Apply.
- Talk to Your Doctor
Download the Discussion Guide
to Start the Conversation Today.
- View T1D Organizations
Stay Connected. Learn About
T1D Organizations Today.
- Get Screened Today
Discover the Importance of Early
Screening. Learn More Now.
- View Patient Stories
Search results
Results From The WOW.Com Content Network
Autoimmune GFAP Astrocytopathy is an autoimmune disease in which the immune system of the patient attacks a protein of the nervous system called glial fibrillary acidic protein (GFAP). It was described in 2016 by researchers of the Mayo Clinic in the United States.
Glial fibrillary acidic protein (GFAP) is a protein that is encoded by the GFAP gene in humans. [5] It is a type III intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS), including astrocytes [ 6 ] and ependymal cells during development. [ 7 ]
An autoantibody—glial fibrillary acidic protein (GFAP)—was found in 2016, in transverse myelitis and atypical NMO, leading to the concept of autoimmune GFAP astrocytopathy. [37] Other autoantibody being researched is flotillin. It has been found in seronegative NMO and some MS patients. [84]
As MS is an active field for research, the list of auto-antibodies is not closed nor definitive. For example, some diseases like Autoimmune GFAP Astrocytopathy or variants of CIDP that affects the CNS (CIDP is the chronic counterpart of Guillain–Barré syndrome) could be included.
In 2016, it was identified in Mayo clinic an autoimmune form of myelitis due to the presence of anti-GFAP autoantibodies. Immunoglobulins directed against the α-isoform of glial fibrillary acidic protein (GFAP-IgG) predicted a special meningoencephalomyelitis termed autoimmune GFAP Astrocytopathy [ 10 ] that later was found also to be able to ...
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease. [67] The importance of this discovery is that the expression of these genes appears in blood and can be measured by a simple blood analysis. NR1H3 Mutation.
Nonvasculitic autoimmune inflammatory meningoencephalitis (NAIM) can be divided into glial fibrillary acidic protein negative (GFAP-) and GFAP positive (GFAP+) cases. [16] The second is related to the autoimmune GFAP astrocytopathy.
Ad
related to: autoimmune gfap