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Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer occurring in about three people per million members of the population. [1] It is also known as cutaneous APUDoma, primary neuroendocrine carcinoma of the skin, primary small cell carcinoma of the skin, and trabecular carcinoma of the skin. [ 2 ]
Singer Jimmy Buffett died of Merkel cell carcinoma, a rare skin cancer, in September. Here’s what to know about the cancer, including symptoms and treatment.
As with all skin cancers, sun exposure is a risk factor, as is a compromised immune system and previous history of skin cancer.
Squamous cell carcinoma. Also known as cutaneous squamous cell carcinoma, this cancer develops when the squamous cells in the top layer of your skin grow out of control. Photos of squamous cell ...
Merkel cells, also known as Merkel–Ranvier cells or tactile epithelial cells, are oval-shaped mechanoreceptors essential for light touch sensation and found in the skin of vertebrates. They are abundant in highly sensitive skin like that of the fingertips in humans , and make synaptic contacts with somatosensory afferent nerve fibers .
The lesion at the base of the keratin mound is benign in the majority of cases. Malignancy is present in up to 20% of cases, with squamous-cell carcinoma being the most common type. The incidence of squamous-cell carcinoma increases to 37% when the cutaneous horn is present on the penis. [3] Cutaneous horn in right ear
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Basal-cell carcinoma: Note the pearly translucency to fleshy color, tiny blood vessels on the surface, and sometimes ulceration which can be characteristics. The key term is translucency. Squamous-cell skin carcinoma: Commonly presents as a red, crusted, or scaly patch or bump. Often a very rapidly growing tumor. Malignant melanoma