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Eplerenone is an antimineralocorticoid, or an antagonist of the mineralocorticoid receptor (MR). [21] Eplerenone is also known chemically as 9,11α-epoxy-7α-methoxycarbonyl-3-oxo-17α-pregn-4-ene-21,17-carbolactone and "was derived from spironolactone by the introduction of a 9α,11α-epoxy bridge and by substitution of the 17α-thoacetyl ...
Eplerenone is a newer drug that was developed as a spironolactone analog with reduced adverse effects. In addition to the y-lactone ring and the substituent on C-7, eplerenone has a 9α,11α-epoxy group. This group is believed to be the reason why eplerenone has a 20-40-fold lower affinity for the mineralocorticoid receptor than spironolactone. [7]
The molecular formula C 24 H 30 O 6 may refer to: Eplerenone , a steroidal antimineralocorticoid of the spirolactone group Estriol triacetate , an estrogen medication and an estrogen ester
Smart meters can also be used in communities who are serviced by standpipes to monitor the flow of water and report leakage or dysfunction. [citation needed] Installation of water management devices in Cape Town, South Africa has led to complaints by residents who perceive this intervention as a draconian, unilateral action by the City. [5]
Freshwater environmental quality parameters are those chemical, physical and biological parameters that can be used to characterise a freshwater body. Because almost all water bodies are dynamic in their composition, the relevant quality parameters are typically expressed as a range of expected concentrations.
Water body temperature is one of the most ubiquitous variables collected in aquatic biomonitoring. Temperatures at the water surface, through the water column, and in the lowest levels of the water body (benthic zone) can all provide insight into different aspects of an aquatic ecosystem. Water temperature is directly affected by climate change ...