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Psoriasis is a long-lasting, noncontagious autoimmune disease characterized by patches of abnormal skin. [4][5] These areas are red, pink, or purple, dry, itchy, and scaly. [8][3] Psoriasis varies in severity from small localized patches to complete body coverage. [3] Injury to the skin can trigger psoriatic skin changes at that spot, which is ...
Medical treatment options for psoriasis generally fall into a few different categories. Topical therapies. These are your creams or lotions (corticosteroids, synthetic forms of vitamin D ...
144 436.68 g·mol −1. Tildrakizumab, sold under the brand name Ilumya among others, is a monoclonal antibody designed for the treatment of immunologically mediated inflammatory disorders. [4] It is approved for the treatment of adults with moderate-to-severe plaque psoriasis in the United States and in the European Union. [2][3][5 ...
Apremilast, sold under the brand name Otezla among others, is a medication for the treatment of certain types of psoriasis and psoriatic arthritis. [4] The drug acts as a selective inhibitor of the enzyme phosphodiesterase 4 (PDE4). [4] It is taken by mouth.
The Rule of Tens is a concept to aid clinicians in making the diagnosis of “severe psoriasis”. [39] It states that a patient is considered to have “severe psoriasis” if their body surface area affected is >10%, or if their Psoriasis Area and Severity Index (PASI) score is >10, or if the DLQI score is >10. [ 39 ]
D10438. Chemical and physical data. Formula. C6402H9864N1676O1994S42. Molar mass. 143 561.59 g·mol −1. Guselkumab, sold under the brand name Tremfya, is a monoclonal antibody against interleukin-23 used for the treatment of plaque psoriasis, psoriatic arthritis, and ulcerative colitis. [7][8][9]
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