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Placement of Cre under control of such a promoter results in localized, tissue-specific expression. As an example, Leone et al. have placed the transcription unit under the control of the regulatory sequences of the myelin proteolipid protein (PLP) gene, leading to induced removal of targeted gene sequences in oligodendrocytes and Schwann cells ...
SST and SST2a receptors are expressed by neurons in the preBötC. Unlike NK1R expression, which remains rather strong in regions caudal to the preBötC within the cervical spinal cord, [9] SST expression appears to peak in the anterior-posterior axis at the region recognized as the preBötC. [11]
Sectional organization of spinal cord. The spinal cord is the main pathway for information connecting the brain and peripheral nervous system. [3] [4] Much shorter than its protecting spinal column, the human spinal cord originates in the brainstem, passes through the foramen magnum, and continues through to the conus medullaris near the second lumbar vertebra before terminating in a fibrous ...
The lateral corticospinal tract (also called the crossed pyramidal tract or lateral cerebrospinal fasciculus) is the largest part of the corticospinal tract.It extends throughout the entire length of the spinal cord, and on transverse section appears as an oval area in front of the posterior column and medial to the posterior spinocerebellar tract.
With the exception of lower muscles of facial expression, all functions of the corticobulbar tract involve inputs from both sides of the brain. [5] The extrapyramidal system refers to tracts within the spinal cord involved in involuntary movement but not part of the pyramidal tracts. [2] Their functions include the control of posture and muscle ...
The corticospinal tract is a white matter motor pathway starting at the cerebral cortex that terminates on lower motor neurons and interneurons in the spinal cord, controlling movements of the limbs and trunk. [1] There are more than one million neurons in the corticospinal tract, and they become myelinated usually in the first two years of life.
The anterior white commissure (ventral white commissure) is a bundle of nerve fibers which cross the midline of the spinal cord just anterior (in front of) to the gray commissure (Rexed lamina X).
Developing neural tube of embryonic mouse shows expression of distinct transcription factors in domains along the dorso-ventral axis of the spinal cord. [37] These domains give rise to distinct population of neurons that have been classified as dorsal (dI1-dI6) and ventral (V0-V3) cardinal classes of spinal interneurons.