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Lithium orotate (C 5 H 3 LiN 2 O 4) is a salt of orotic acid and lithium.It is available as the monohydrate, LiC 5 H 3 N 2 O 4 ·H 2 O. [1] In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissolves in solution to produce free lithium ions.
7), lithium sulfate, lithium chloride, and lithium orotate. [ 139 ] [ 140 ] Nanoparticles and microemulsions have also been invented as drug delivery mechanisms. As of 2020, there is a lack of evidence that alternate formulations or salts of lithium would reduce the need for monitoring serum lithium levels or lower systemic toxicity.
Orotic acid is a Bronsted acid and its conjugate base, the orotate anion, is able to bind to metals. Lithium orotate, for example, has been investigated for use in treating alcoholism, [4] [5] and complexes of cobalt, manganese, nickel, and zinc are known. [6]
The Autoimmune Protocol (AIP) diet is an elimination diet designed to help reduce inflammation, manage symptoms and improve quality of life for people with autoimmune diseases.
However, adding more plants to your diet can have major heart-health benefits. For convenience, think canned beans, prewashed spinach, berries, and whole-grain bread, pasta and cereal.
The beauty of this is that it’s easy to incorporate into your post-meal routine and you don’t have to spend hours hitting the pavement to reap these benefits.