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  2. Management of thalassemia - Wikipedia

    en.wikipedia.org/wiki/Management_of_thalassemia

    Betibeglogene autotemcel, sold under the brand name Zynteglo, is a gene therapy for the treatment for beta thalassemia. [32] It was approved for medical use in the European Union in May 2019, [33] and in the United States in August 2022.

  3. Beta thalassemia - Wikipedia

    en.wikipedia.org/wiki/Beta_thalassemia

    Patients with beta thalassemia minor are usually asymptomatic and are often monitored without treatment. [8] Beta thalassemia minor may coexist with other conditions such as chronic hepatitis B, chronic hepatitis C, non-alcoholic fatty liver disease and alcoholic liver disease that, when combined or co-existing, may cause a person to have iron ...

  4. Thalassemia - Wikipedia

    en.wikipedia.org/wiki/Thalassemia

    There are two approved forms of gene therapy for beta thalassemia. [96] [97] Betibeglogene autotemcel, sold under the brand name Zynteglo, is a gene therapy for the treatment for beta thalassemia which adds a healthy beta-globin gene to the HSCs. [98] It was approved for medical use in the United States in August 2022.

  5. Luspatercept - Wikipedia

    en.wikipedia.org/wiki/Luspatercept

    Luspatercept, sold under the brand name Reblozyl, is a medication used for the treatment of anemia in beta thalassemia and myelodysplastic syndromes. [5] The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. [8]

  6. List of hematologic conditions - Wikipedia

    en.wikipedia.org/wiki/List_of_hematologic_conditions

    Beta-thalassemia: D56.1: 3087: Beta-thalassemia (β-thalassemia) is an autosomal dominant blood condition that results in the reduction of hemoglobin production. The cause for the disorder is related to a genetic mutation of the HBB gene. This gene is responsible for providing the instructions to produce beta-globin; one of the major components ...

  7. Transfusion-dependent anemia - Wikipedia

    en.wikipedia.org/wiki/Transfusion-dependent_anemia

    Side effects include iron overloading, [12] [4] [9] [13] [5] allergic reactions that lead to skin rashes and infections transmitted through transfusion. [4] [12] The most common side effect is iron overloading, which the severity of overload depends on the frequency, volume, and the amount of blood transfused to the patient. [9]

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