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Dose adjustment is required in the elderly and in those with renal impairment. [3] Ciprofloxacin is weakly bound to serum proteins (20–40%). It is an inhibitor of the drug-metabolizing enzyme cytochrome P450 1A2, which leads to the potential for clinically important drug interactions with drugs metabolized by that enzyme. [5]
Narrow-spectrum antibiotics have low propensity to induce bacterial resistance and are less likely to disrupt the microbiome (normal microflora). [3] On the other hand, indiscriminate use of broad-spectrum antibiotics may not only induce the development of bacterial resistance and promote the emergency of multidrug-resistant organisms, but also cause off-target effects due to dysbiosis.
The following is a list of antibiotics. The highest division between antibiotics is bactericidal and bacteriostatic . Bactericidals kill bacteria directly, whereas bacteriostatics prevent them from dividing.
Health care prescribers and pharmacists also check to make sure the antibiotic is prescribed at the correct dose and duration, she says, and “they look for potential issues like drug ...
Ciprofloxacin: Fluoroquinolone antibiotic: ... Legal status: Investigational; Ciprofloxacin/celecoxib or PrimeC is a fixed-dose combination of ciprofloxacin and ...
A new study in mouse models of inflammatory bowel disease (IBD) suggests that common antibiotics may increase the risk of developing a form of IBD by damaging the protective mucus layer of the gut.
Quinolone antibiotics constitute a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. [1] They are used in human and veterinary medicine to treat bacterial infections , as well as in animal husbandry , specifically poultry production .
This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class. Antibiotics are listed alphabetically within their class or subclass by their nonproprietary name. If an antibiotic is a combination drug, both ingredients will be listed.