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Terbinafine is an antifungal medication used to treat pityriasis versicolor, fungal nail infections, and ringworm including jock itch and athlete's foot. [ 1 ] [ 2 ] [ 3 ] It is either taken by mouth or applied to the skin as a cream or ointment.
Examples of allylamines antifungals comprise amorolfin, naftifine and terbinafine. The last group consists of antifungal drugs with a different mechanism of action than the other three classes. These drugs include benzoxaborole antifungals, ciclopirox olamine antifungals, thiocarbamate antifungals and undecylenic alkanolamide antifungals ...
The effects last because grapefruit-mediated inhibition of drug metabolizing enzymes, like CYP3A4, is irreversible; [30] that is, once the grapefruit has "broken" the enzyme, the intestinal cells must produce more of the enzyme to restore their capacity to metabolize drugs that the enzyme is used to metabolize. [19]
An example is tinea pedis; this is sometimes treated with topical terbinafine. [5] Oral ... This page was last edited on 3 December 2024, at 00:50 (UTC).
Onychomycosis does not necessarily require treatment. [3] The antifungal medication terbinafine taken by mouth appears to be the most effective but is associated with liver problems. [2] [5] Trimming the affected nails when on treatment also appears useful. [2] There is a ciclopirox-containing nail polish, but there is no evidence that it works ...
As of 2012, research has shown that terbinafine is 2.26 times as likely to cure athlete's foot than treatment with Griseofulvin; comparative studies between itraconazole and terbinafine have shown little difference in effectiveness. [37]
Tavaborole, sold under the brand name Kerydin, is a topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed with a complete clearance rate of 6-7% and partial clearance rate of 23-24% in individuals whose “infection border does not reach the cuticle at the base of the large toenail.” [1] Tavaborole was approved by the US FDA in July ...
Treatment is with long-term systemic antifungals, typically oral terbinafine or itraconazole. [4] [8] The condition is frequently seen in skin clinics. [9] Males are affected more frequently than females. [3] One study showed that 65% of cases with tinea manuum were part of TFOHS. [6] [10] TFOHS was first described by Curtis in 1964. [11]