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Gestational age: 12 weeks and 0 days until 15 weeks and 6 days old. Embryonic age: 10 weeks and 0 days until 13 weeks and 6 days old. The fetus reaches a length of about 15 cm (6 in). A fine hair called lanugo develops on the head. Fetal skin is almost transparent. More muscle tissue and bones have developed, and the bones become harder.
The first ten weeks of gestational age is the period of embryogenesis and together with the first three weeks of prenatal development make up the first trimester of pregnancy. From the 10th week of gestation (8th week of development), the developing embryo is called a fetus.
The third trimester is defined as starting, between the beginning of week 28 (27 weeks + 0 days of GA) [36] or beginning of week 29 (28 weeks + 0 days of GA). [4] It lasts until childbirth . Timeline of pregnancy, including (from top to bottom): Trimesters, embryo/fetus development, gestational age in weeks and months, viability and maturity stages
Human embryonic development covers the first eight weeks of development, which have 23 stages, called Carnegie stages. At the beginning of the ninth week, the embryo is termed a fetus (spelled "foetus" in British English). In comparison to the embryo, the fetus has more recognizable external features and a more complete set of developing organs.
The volume of amniotic fluid changes with the growth of fetus. From the tenth to the 20th week it increases from 25 to 400 millilitres (0.88 to 14.08 imp fl oz; 0.85 to 13.53 US fl oz) approximately. [3] Approximately in the 10th–11th week, the breathing and swallowing of the fetus slightly decrease the amount of fluid.
An ultrasound showing an embryo measured to have a crown-rump length of 1.67 cm and estimated to have a gestational age of 8 weeks and 1 day. Crown-rump length (CRL) is the measurement of the length of human embryos and fetuses from the top of the head (crown) to the bottom of the buttocks (rump).
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Linear growth is a complex process regulated by the growth hormone (GH) – insulin-like growth factor-1 axis, the thyroxine/triiodothyronine axis, androgens, estrogens, vitamin D, glucocorticoids and possibly leptin. [25] GH is secreted by the anterior pituitary gland in response to hypothalamic, pituitary and circulating factors.