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PCP is self-administered and induces ΔFosB expression in the D1-type medium spiny neurons of the nucleus accumbens, [3] [26] and accordingly, excessive PCP use is known to cause addiction. [3] PCP's rewarding and reinforcing effects are at least partly mediated by blocking the NMDA receptors in the glutamatergic inputs to D1-type medium spiny ...
Pentachlorophenol (PCP) is an organochlorine compound used as a pesticide and a disinfectant. First produced in the 1930s, it is marketed under many trade names. [5] It can be found as pure PCP, or as the sodium salt of PCP, the latter of which dissolves easily in water. It can be biodegraded by some bacteria, including Sphingobium ...
PCPr is an arylcyclohexylamine dissociative anesthetic drug with hallucinogenic and stimulant effects. It is around the same potency as phencyclidine, although slightly less potent than the ethyl homologue eticyclidine, [1] and has reportedly been sold as a designer drug in Germany and other European countries since the late 1990s.
Bath salts usually contain cathinones, typically methylenedioxypyrovalerone (MDPV, also known as "monkey dust", although this term can refer to MDPHP as well [8]), methylone or mephedrone; however, the chemical composition varies widely [6] [9] and products labeled with the same name may also contain derivatives of pyrovalerone or pipradrol.
The last image we have of Patrick Cagey is of his first moments as a free man. He has just walked out of a 30-day drug treatment center in Georgetown, Kentucky, dressed in gym clothes and carrying a Nike duffel bag.
Wolford and Roman Mendez, 6, were both shot at the Feather River School of Seventh-Day Adventists in Butte County on December 4, 2024. Six-year-old Roman Mendez (left) and 5-year-old Elias Wolford ...
Olney's lesions, also known as NMDA receptor antagonist neurotoxicity (NAT), is a form of brain damage consisting of selective death of neurons but not glia, observed in restricted brain regions of rats and certain other animal models exposed to large quantities of psychoactive drugs that inhibit the normal operation of the neuronal NMDA receptor.
5. You’re Gaining Weight Unintentionally. While protein is often associated with weight loss, eating too much can have the opposite effect. “Consuming more protein than your body needs can ...