Ads
related to: breast cancer molecular targeted therapy of glioblastoma
Search results
Results From The WOW.Com Content Network
There are targeted therapies for lung cancer, colorectal cancer, head and neck cancer, breast cancer, multiple myeloma, lymphoma, prostate cancer, melanoma and other cancers. [ 1 ] [ 4 ] [ 5 ] Biomarkers are usually required to aid the selection of patients who will likely respond to a given targeted therapy.
In 2015, a phase I clinical trial of PAC-1 opened for enrollment of cancer patients, and in 2016, it was announced that PAC-1 had been granted Orphan Drug Designation for treatment of glioblastoma by the FDA, and in late 2017 a Phase 1b trial began of PAC-1 plus temozolomide for treatment of patients with recurrent glioblastoma or anaplastic ...
Bevacizumab, sold under the brand name Avastin among others, is a monoclonal antibody medication used to treat a number of types of cancers and a specific eye disease. [30] [28] For cancer, it is given by slow injection into a vein (intravenous) and used for colon cancer, lung cancer, ovarian cancer, glioblastoma, hepatocellular carcinoma, and renal-cell carcinoma. [31]
Sonidegib has been effective in limiting the invasive potential of multiple cancer types including glioblastoma, [38] prostate cancer, [39] and renal cell carcinoma. [40] It received FDA approval in July 2015 and is being used for the treatment of BCC that has recurred post-surgery or post-radiation therapy.
Particularly the deletion of the gene p16 in conjunction with the whole or partial deletion of MTAP has been indicated in some cancer types. [19] Genes p15 and p16 of chromosome nine are closely linked to the MTAP gene, because of this, MTAP is commonly cross-deleted. [12] [13] [19] This deletion is found in many cancerous tissues. [12] [13]
The classification of genetic breast cancer subtypes, including triple-negative and HER2-positive subtypes, [8] have allowed oncologists to use a patient’s breast cancer subtype to personalize cancer therapy schedules.
Ads
related to: breast cancer molecular targeted therapy of glioblastoma