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3,4,5-Trimethoxybenzaldehyde can be used as an intermediate in the synthesis of some pharmaceutical drugs including trimethoprim, [1] [2] cintriamide, roletamide, trimethoquinol (aka tretoquinol), and trimazosin as well as some psychedelic phenethylamines.
Eudesmic acid is most directly synthesized by reaction of gallic acid with dimethyl ... Trimebutine; Amoproxan; Bernzamide; 3,4,5-trimethoxy-N-(pyridin-4-yl)benzamide ...
Benzamide is an organic compound with the chemical formula of C 7 H 7 NO. It is the simplest amide derivative of benzoic acid. In powdered form, it appears as a white solid, while in crystalline form, it appears as colourless crystals. [5] It is slightly soluble in water, [2] and soluble in many organic solvents. [6]
Trimethobenzamide synthesis: Hoffmann La Roche, U.S. patent 2,879,293 (1959). Alkylation of the sodium salt of p-hydroxybenzaldehyde (1) with 2-dimethylaminoethyl chloride affords the ether (2).
Benzimidazole is a base: . C 6 H 4 N(NH)CH + H + → [C 6 H 4 (NH) 2 CH] +. It can also be deprotonated with stronger bases: . C 6 H 4 N(NH)CH + LiH → Li [C 6 H 4 N 2 CH] + H 2. The imine can be alkylated and also serves as a ligand in coordination chemistry.
Orcinol (5-methylbenzene-1,3-diol) Methoxyphenols — can be derived from benzenediols by O-methylation. Guaiacol (2-methoxyphenol, O-Methylcatechol) Mequinol (4-Methoxyphenol) Dimethoxybenzenes — can be derived from benzenediols by two rounds of O-methylation. Veratrole (1,2-Dimethoxybenzene) 1,3-Dimethoxybenzene; 1,4-Dimethoxybenzene
3,5-Dimethylpyrazole is an organic compound with the formula (CH 3 C) 2 CHN 2 H. It is one of several isomeric derivatives of pyrazole that contain two methyl substituents. The compound is unsymmetrical but the corresponding conjugate acid (pyrazolium) and conjugate base (pyrazolide) have C 2v symmetry. It is a white solid that dissolves well ...
Amidoximes are oximes of amides (R 1 C(=O)NR 2 R 3) with general structure R 1 C(=NOH)NR 2 R 3. Oximes are usually generated by the reaction of hydroxylamine with aldehydes (R−CH=O) or ketones (RR’C=O). The term oxime dates back to the 19th century, a combination of the words oxygen and imine. [1]