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CA19-9 can be elevated in many types of gastrointestinal cancer, such as colorectal cancer, esophageal cancer and hepatocellular carcinoma. [1] Apart from cancer, elevated levels may occur in pancreatitis, cirrhosis, [1] and diseases of the bile ducts. [1] [3] It can also be elevated in people with obstruction of the bile ducts. [3]
230099 Ensembl ENSG00000107159 ENSMUSG00000028463 UniProt Q16790 Q8VHB5 RefSeq (mRNA) NM_001216 NM_139305 RefSeq (protein) NP_001207 NP_647466 Location (UCSC) Chr 9: 35.67 – 35.68 Mb Chr 4: 43.51 – 43.51 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Carbonic anhydrase IX (CA9/CA IX) is an enzyme that in humans is encoded by the CA9 gene. It is one of the 14 carbonic anhydrase ...
breast cancer [11] CA19-9: Mainly pancreatic cancer, but also colorectal cancer and other types of gastrointestinal cancer. [12] CA-125: Mainly ovarian cancer, [13] but may also be elevated in for example endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer. [14] Calcitonin: medullary thyroid ...
Esophageal cancer is the eighth-most frequently-diagnosed cancer worldwide, [2] and because of its poor prognosis, it is the sixth most-common cause of cancer-related deaths. [55] It caused about 400,000 deaths in 2012, accounting for about 5% of all cancer deaths (about 456,000 new cases were diagnosed, representing about 3% of all cancers).
With treatment, typical survival with CUP ranges from 6 to 16 months. [7] Survival rates are lower in cases with visceral metastatic disease, ranging from 6 to 9 months. [7] Survival rates are higher when the cancer is more limited to lymph nodes, pleura, or peritoneal metastasis, which ranges from 14 to 16 months. [7]
In the United States there has been an increase in the 5-year relative survival rate between people diagnosed with cancer in 1975-1977 (48.9%) and people diagnosed with cancer in 2007-2013 (69.2%); these figures coincide with a 20% decrease in cancer mortality from 1950 to 2014. [8]