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The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermis layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.
Merkel cells are found in the skin and some parts of the mucosa of all vertebrates. In mammalian skin, they are clear cells found in the stratum basale [2] [3] (at the bottom of sweat duct ridges) of the epidermis approximately 10 μm in diameter. They are oval-shaped mechanoreceptors essential for light touch sensation and found in the skin of ...
The neural crest is a ridge-like structure that is formed transiently between the epidermal ectoderm and neural plate during vertebrate development. Neural crest cells originate from this structure through the epithelial-mesenchymal transition, and in turn give rise to a diverse cell lineage—including melanocytes, craniofacial cartilage and bone, smooth muscle, dentin, peripheral and enteric ...
The epidermis, "epi" coming from the Greek language meaning "over" or "upon", is the outermost layer of the skin. It forms the waterproof, protective wrap over the body's surface, which also serves as a barrier to infection and is made up of stratified squamous epithelium with an underlying basal lamina.
The apical ectodermal ridge (AER) is a structure that forms from the ectodermal cells at the distal end of each limb bud and acts as a major signaling center to ensure proper development of a limb. After the limb bud induces AER formation, the AER and limb mesenchyme —including the zone of polarizing activity (ZPA)—continue to communicate ...
The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
This undated photo released by the New York Police Department shows a suspect in the fatal shooting of UnitedHealthcare CEO Brian Thompson on Dec. 4, 2024, in a taxi.
Eimer's organs are organs for the sense of touch, shaped like bulbous papillae, formed from modified epidermis.First isolated by Theodor Eimer from the European mole in 1871, these organs are present in many moles, and are particularly dense on the star-nosed mole, which bears 25,000 of them on its unique tentacled snout.