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Moraxella catarrhalis is a fastidious, nonmotile, Gram-negative, aerobic, oxidase-positive diplococcus that can cause infections of the respiratory system, middle ear, eye, central nervous system, and joints of humans. It causes the infection of the host cell by sticking to the host cell using trimeric autotransporter adhesins.
Examples of gram-negative diplococci are Neisseria spp. and Moraxella catarrhalis. Examples of gram-positive diplococci are Streptococcus pneumoniae and Enterococcus spp. [10] [11] Presumably, diplococcus has been implicated in encephalitis lethargica. [12] The genus Neisseria belongs to the family Neisseriaceae.
Moraxella is a genus of gram-negative bacteria in the family Moraxellaceae. It is named after the Swiss ophthalmologist Victor Morax . The organisms are short rods , coccobacilli , or as in the case of Moraxella catarrhalis , diplococci in morphology, with asaccharolytic, oxidase -positive, and catalase -positive properties. [ 2 ]
"Atypical pneumonia" is atypical in that it is caused by atypical organisms (other than Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis). [20] These atypical organisms include special bacteria, viruses, fungi, and protozoa.
Moraxella catarrhalis and Acinetobacter baumannii are human pathogens, and Moraxella bovis is the cause of "pinkeye" of cattle (infectious bovine keratoconjunctivitis ...
Gram-negative bacteria are seen less frequently: Haemophilus influenzae , Klebsiella pneumoniae , Escherichia coli , Pseudomonas aeruginosa , Bordetella pertussis, and Moraxella catarrhalis are the most common. These bacteria often live in the gut and enter the lungs when contents of the gut (such as vomit or faeces) are inhaled.
The most common organisms which cause lobar pneumonia are Streptococcus pneumoniae, also called pneumococcus, Haemophilus influenzae and Moraxella catarrhalis. Mycobacterium tuberculosis, the tubercle bacillus, may also cause lobar pneumonia if pulmonary tuberculosis is not treated promptly.
UspA1 is another example of a Trimeric Autotransporter Adhesin found in the bacterium Moraxella catarrhalis, found as a common cause of middle ear infections in humans. The structure of UspA1 also has a head domain at N-terminal domain, however it is folded into the beta propeller.