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[2] [10] When used by people with liver problems, and in elderly individuals, doses should be reduced. [10] Amlodipine works partly by vasodilation (relaxing the arteries and increasing their diameter). [10] It is a long-acting calcium channel blocker of the dihydropyridine type. [10] Amlodipine was patented in 1982, and approved for medical ...
AKI - the other main type of kidney disease - can be caused by dehydration, blood loss, urinary tract obstructions such as kidney stones or blood clots, low blood pressure, or heart disease. It ...
Thus they are commonly present in many people's homes. In young children one pill may cause serious health problems and potentially death. [8] The calcium channel blocker that caused the greatest number of deaths in 2010 in the United States was verapamil. [2] This agent is believed to cause more heart problems than many of the others. [2]
There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity. Nephrotoxicity should not be confused with some medications predominantly excreted by the kidneys needing their dose adjusted for the decreased kidney function (e.g., heparin, lithium).
Beta blockers can trigger or worsen psoriasis, psoriatic arthritis, and rheumatoid arthritis. [62] Benign prostatic hyperplasia may be improved with the use of an alpha blocker. Chronic kidney disease. ACEis or ARBs should be included in the treatment plan to improve kidney outcomes regardless of race or diabetic status. [7] [16]
The risk of high blood potassium is greater in those with kidney problems, diabetes, and those who are older. [1] Amiloride blocks the epithelial sodium channel (ENaC) in the late distal tubule, connecting tubule, and collecting duct of the nephron , [ 3 ] which both reduces absorption of sodium ion from the lumen of the nephron and reduces ...