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Low-dose spironolactone is generally very well tolerated. [63] Even higher doses of spironolactone, such as 100 mg/day, are well tolerated in most individuals. [63] Dose-dependent side effects of spironolactone include menstrual irregularities, breast tenderness, and enlargement, orthostatic hypotension, and hyperkalemia. [63]
[28] [16] In addition, the AR antagonism of spironolactone is involved in its feminizing side effects, such as gynecomastia in men. [28] Spironolactone has been found to produce gynecomastia without changes in testosterone or estradiol levels, implicating AR antagonism in this side effect. [30] Gynecomastia is a major known side effect of AR ...
Potassium-sparing diuretics or antikaliuretics [1] refer to drugs that cause diuresis without causing potassium loss in the urine. [2] They are typically used as an adjunct in management of hypertension, cirrhosis, and congestive heart failure. [3] The steroidal aldosterone antagonists can also be used for treatment of primary hyperaldosteronism.
It is also the case for the maximum dose of Ozempic for weight loss. ... start on the maximum 2.0 mg weekly dose. Instead, your healthcare provider will begin with 0.25 mg once-weekly doses ...
This can be overwhelming, from looking up hair loss treatments to scouring social media. When you start losing hair, Google quickly becomes your trusted advisor as you head toward Spiral City ...
Unlike spironolactone, bicalutamide has no antimineralocorticoid activity, [97] and for this reason, has no risk of hyperkalemia (which can, rarely/in severe cases, result in hospitalization or death) [112] or other antimineralocorticoid side effects such as urinary frequency, dehydration, hypotension, hyponatremia, metabolic acidosis, or ...