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In acute bacterial sialadenitis, acinar destruction with interstitial neutrophil infiltrates is observed. Small abscesses with necrosis are common. In viral sialadenitis, vacuolar changes are seen in the acini with lymphocytic and monocytic infiltrate found in the interstitium. Cytomegalovirus (CMV) sialadenitis may show no gross symptoms.
Infections involving the salivary glands can be viral or bacterial (or rarely fungal). Mumps is the most common viral sialadenitis. It usually occurs in children and involves pain in front of the ear, swelling of the parotid, fever, chills, and headaches. [2] Bacterial sialadenitis is usually caused by ascending organisms from the mouth.
Chronic sclerosing sialadenitis is a chronic (long-lasting) inflammatory condition affecting the salivary gland. Relatively rare in occurrence, this condition is benign, but presents as hard, indurated and enlarged masses that are clinically indistinguishable from salivary gland neoplasms or tumors.
Up to 80 percent of dogs infected will have symptoms, but the mortality rate is only 5 to 8 percent. [5] Infectious canine hepatitis is a sometimes fatal infectious disease of the liver. [6] Canine herpesvirus is an infectious disease that is a common cause of death in puppies less than three weeks old. [7]
The usual symptoms are pain and swelling of the affected salivary gland, both of which get worse when salivary flow is stimulated, e.g. with the sight, thought, smell or taste of food, or with hunger or chewing. This is often termed "mealtime syndrome." [2] Inflammation or infection of the gland may develop as a result.
Kennel cough is so named because the infection can spread quickly among dogs in the close quarters of a kennel or animal shelter. Viral and bacterial causes of canine cough are spread through airborne droplets produced by sneezing and coughing. These agents also spread through contact with contaminated surfaces.