Search results
Results From The WOW.Com Content Network
Replication (statistics) In engineering, science, and statistics, replication is the process of repeating a study or experiment under the same or similar conditions to support the original claim, which crucial to confirm the accuracy of results as well as for identifying and correcting the flaws in the original experiment. [1]
Reproducibility. Reproducibility, closely related to replicability and repeatability, is a major principle underpinning the scientific method. For the findings of a study to be reproducible means that results obtained by an experiment or an observational study or in a statistical analysis of a data set should be achieved again with a high ...
The PDF of the paper. " Why Most Published Research Findings Are False " is a 2005 essay written by John Ioannidis, a professor at the Stanford School of Medicine, and published in PLOS Medicine. [1] It is considered foundational to the field of metascience. In the paper, Ioannidis argued that a large number, if not the majority, of published ...
Ioannidis (2005): "Why Most Published Research Findings Are False". [1] The replication crisis[a] is an ongoing methodological crisis in which the results of many scientific studies are difficult or impossible to reproduce. Because the reproducibility of empirical results is an essential part of the scientific method, [2] such failures ...
Design of experiments. The design of experiments (DOE or DOX), also known as experiment design or experimental design, is the design of any task that aims to describe and explain the variation of information under conditions that are hypothesized to reflect the variation. The term is generally associated with experiments in which the design ...
The Meselson–Stahl experiment is an experiment by Matthew Meselson and Franklin Stahl in 1958 which supported Watson and Crick 's hypothesis that DNA replication was semiconservative. In semiconservative replication, when the double-stranded DNA helix is replicated, each of the two new double-stranded DNA helices consisted of one strand from ...
The replication fork is a structure that forms within the long helical DNA during DNA replication. It is produced by enzymes called helicases that break the hydrogen bonds that hold the DNA strands together in a helix. The resulting structure has two branching "prongs", each one made up of a single strand of DNA.
Hershey–Chase experiment. The Hershey–Chase experiments were a series of experiments conducted in 1952 [1] by Alfred Hershey and Martha Chase that helped to confirm that DNA is genetic material. While DNA had been known to biologists since 1869, [2] many scientists still assumed at the time that proteins carried the information for ...