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“Take water-soluble vitamins on an empty stomach with a glass of water,” recommends Dr. Perez-Gallardo. And since it can be energizing, Dr. Perez-Gallardo says that the best time to take vitamin B12 is in the morning, so it won’t affect your sleep. When is the best time to take vitamin D and other fat-soluble vitamins?
If you are unable to get sufficient vitamin B12 from food and need to take a supplement, the best time to take B12 is with a meal and preferably in the morning.
In the case of water-soluble vitamins like B12, vitamin C, folic acid, and other B vitamins, some medically reviewed literature points to early morning as the optimal time to take them as they can be taken on an empty stomach, but more peer-reviewed research is needed to confirm this claim.
You should take vitamin B12, or mecobalamin, in the morning with breakfast. You can take it before bed, but taking B12 at night could disrupt your sleep.
The best time to take vitamin B12 is early in the day, first thing in the morning or with breakfast. It doesn’t matter much if you take it with a meal or on an empty stomach, but it may be best absorbed on an empty stomach by avoiding food interactions.
For example, it's better to take vitamin B12 in the morning for this reason. It's also important to take vitamin B6 during the day. When taken at night, it can interfere with sleep and cause vivid dreams.
Wondering when to take a B complex supplement? Experts recommend adding it to your morning routine and taking it on an empty stomach with a glass of water.
Always take B12 supplements with a full glass of water to optimize absorption. You may also want to take vitamin B12 in the morning, because it’s known to boost your energy and could interfere with your sleep if you take it at night.
According to health experts at Click Pharmacy, as a general rule of thumb, take your B vitamins in the morning or with a meal. Vitamin B12, for example, should definitely be taken in the morning. This is because it is important for energy metabolism, which may interrupt your sleep if taken at night.
While the timing of intake holds significance, it’s equally critical to know when not to take B12. As a rule of thumb, avoid consuming B12 late in the evening or right before sleep. Downplaying its night owl tendencies, B12 is a vitamin best not taken before hitting the hay.