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Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [3]
Toxicology. Causes. Excessive consumption of vitamins. Hypervitaminosis is a condition of abnormally high storage levels of vitamins, which can lead to various symptoms as over excitement, irritability, or even toxicity. Specific medical names of the different conditions are derived from the given vitamin involved: an excess of vitamin A, for ...
Registered dietitians explain what vitamin B12 is, how much you need, and the potential side effects of taking too much. Skip to main content. 24/7 Help. For premium support please call: ...
Serum vitamin B12. Serum vitamin B12 is a medical laboratory test that measure vitamin B 12 only in the blood binding to both transcobalamins. [1] Most of the time, 80–94% of vitamin B 12 in the blood binds to haptocorrin, while only 6–20% is binds to transcobalamin ll. [2] Only transcobalamin ll is "active" and can be used by the body. [1]
One of the superpowers of vitamin B12 is that it is the only water-soluble vitamin that can be stored in the human body, Kitchens points out, and it can remain stored in the liver for several years.
6% (< 60 years old), 20% (> 60 years old) [ 4 ] Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [ 5 ] Symptoms can vary from none to severe. [ 1 ] Mild deficiency may have few or absent symptoms. [ 1 ]
Pernicious anaemia is a lifelong condition that affects nearly 5 in 100,000 people in the UK.
No overdosage or toxicity has been reported with this drug. [2] Hydroxocobalamin is the natural form of vitamin B 12 and a member of the cobalamin family of compounds. [6][7] It is found in both raw and cooked beef, together with other cobalamins. [8] Hydroxocobalamin, or another form of vitamin B 12, are required for the body to make DNA.