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Usual Adult Dose for Depression. Initial dose: 150 mg orally per day in divided doses; this may be increased by 50 mg orally per day every 3 to 4 days. Maximum dose: Inpatients: 600 mg/day. Outpatients: 400 mg/day. Comments:
Adults—At first, 150 milligrams (mg) per day, given in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. If you miss a dose of this medicine, take it as soon as possible.
Generic name: trazodone [ TRAZ-oh-done ] Brand names: Desyrel, Desyrel Dividose, Oleptro. Dosage form: oral tablet (100 mg; 150 mg; 300 mg; 50 mg) Drug class: Phenylpiperazine antidepressants. Medically reviewed by Melisa Puckey, BPharm. Last updated on Feb 29, 2024.
The typical trazodone dosage for depression is up to 400 mg per day in divided doses. For insomnia, the dose is usually lower — between 25 mg and 100 mg before bedtime. If you’re an older adult or you take medications that interact with trazodone, you may need a lower trazodone dosage.
Trazodone is most often prescribed at doses between 25mg to 100mg as a sleep aid. However, studies show lower dosages of trazodone are effective and may cause less daytime sleepiness and...
Your doctor may advise you to take your dose of trazodone once a day. If you have a larger dose, your doctor may suggest that you split it and take it twice a day. If your dose is 300mg a day or less, your doctor will probably tell you to take it as a single dose at bedtime.
Dosing: Geriatric. Major depressive disorder (unipolar) (alternative agent): Immediate release: Oral: Initial: 25 to 50 mg at bedtime; may increase in increments of 25 to 50 mg/day every 3 days for inpatients and weekly for outpatients, if tolerated; usual dose: 75 to 150 mg/day.
A typical starting dose of trazodone for treating major depressive disorder (MDD) is 150 mg daily divided into 2 to 3 separate doses. Every 3 or 4 days, your prescriber can increase your dose by 50mg, depending on individual response. The maximum dose of trazodone used for outpatients is 400 mg daily.
What Are Dosages of Trazodone? Adult dosage. Tablet, extended-release. Depression. Adult dosage. Oleptro (extended-release) Pediatric Depression Treatment (Off-label) Geriatric Depression Treatment. Insomnia (Off-label) 50-100 mg orally once per day. Aggressive Behavior (Off-label) Initial: 50 mg orally every 12 hours.
Why it’s used. Trazodone is used to treat depression in adults. How it works. Trazodone belongs to a class of drugs called antidepressants. A class of drugs is a group of medications that work...