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Phytomenadione, also known as vitamin K 1 or phylloquinone, is a vitamin found in food and used as a dietary supplement. [6] [7] It is on the World Health Organization's List of Essential Medicines. [8] It is used to treat certain bleeding disorders, [7] including warfarin overdose, vitamin K deficiency, and obstructive jaundice. [7]
The menadione core is apparent in the structure of vitamin K. It is an intermediate in the chemical synthesis of vitamin K by first reduction to the diol menadiol, which is susceptible to coupling to the phytol. [10] It is a useful intermediate for organic synthesis in general, as it can be made and modified in a number of ways. [11]
Additional risk factors include 1) infants who never got a vitamin K shot at birth, even more so if they were solely breastfed, 2) infants who had mothers taking medications to treat seizures since these affect how the body uses vitamin K, 3) infants with diarrhea, cystic fibrosis, and celiac disease because this makes it hard to absorb ...
Until Bangladesh Liberation War in 1971, the Pakistani rupee was the currency of the country. The Bangladeshi currency was first issued on March 4, 1972 after Bangladesh gained independence. [2] The official currency was named Taka, later "৳" was designated as the symbol of Taka. The minimum unit of money fixed is one rupee.
The first treasury notes in 1972 for ৳ 1 and notes of the Bangladesh Bank for ৳ 5, ৳ 10 and ৳ 100. In 1977, banknotes for ৳ 50 were introduced, followed by ৳ 500 in 1979 and ৳ 20 in 1982. ৳ 1 treasury notes were issued until 1992, with ৳ 2 treasury notes introduced in 1989. ৳ 1000 banknotes were introduced in 2008.
Until Bangladesh Liberation War in 1971, the Pakistani Rupee was the Currency of the country. Bangladeshi currency was first issued on March 4, 1972 after the Independence of Bangladesh. [2] The official currency was named Taka, later "৳" was designated as the symbol of Taka. The minimum unit of money fixed is one taka.
Newborn infants have low stores of vitamin K, and human breast milk has low concentrations of the vitamin. This combination can lead to vitamin K deficiency and later onset bleeding. Vitamin K deficiency leads to the risk of blood coagulation problems due to impaired production of clotting factors II, VII, IX, X, protein C and protein S by the ...
Vitamin K 1-deficiency may occur by disturbed intestinal uptake (such as would occur in a bile duct obstruction), by therapeutic or accidental intake of a vitamin K 1-antagonist such as warfarin, or, very rarely, by nutritional vitamin K 1 deficiency. As a result, Gla-residues are inadequately formed and the Gla-proteins are insufficiently active.