Search results
Results From The WOW.Com Content Network
The best known explanation of the oxygen effect is the oxygen fixation hypothesis developed by Alexander in 1962, [9] which posited that radiation-induced non-restorable or "fixed" nuclear DNA lesions are lethal to cells in the presence of diatomic oxygen. [10] [11] Recent hypotheses include one based on oxygen-enhanced damage from first ...
Excessive exposure to oxygen can lead to oxygen toxicity, also known as oxygen toxicity syndrome, oxygen intoxication, and oxygen poisoning.There are two main ways in which oxygen toxicity can occur: exposure to significantly elevated partial pressures of oxygen for a short period of time (acute oxygen toxicity), or exposure to more modest elevations in oxygen partial pressures but for a ...
Aerobic respiration requires oxygen (O 2) in order to create ATP.Although carbohydrates, fats and proteins are consumed as reactants, aerobic respiration is the preferred method of pyruvate production in glycolysis, and requires pyruvate be transported the mitochondria in order to be oxidized by the citric acid cycle.
The oxygen–hemoglobin dissociation curve, also called the oxyhemoglobin dissociation curve or oxygen dissociation curve (ODC), is a curve that plots the proportion of hemoglobin in its saturated (oxygen-laden) form on the vertical axis against the prevailing oxygen tension on the horizontal axis. This curve is an important tool for ...
Table 1 gives the example of a typical oxygen cascade for skeletal muscle of a healthy, adult male at rest who is breathing air at atmospheric pressure at sea level. Actual values in a person may vary widely due to ambient conditions, health status, tissue type, and metabolic demands.
More generally, in the medical literature, the Pasteur effect refers to how the cellular presence of oxygen causes in cells a decrease in the rate of glycolysis and also a suppression of lactate accumulation. The effect occurs in animal tissues, as well as in microorganisms belonging to the fungal kingdom. [2] [3]
Rather than combustion, organisms rely on elaborate sequences of electron-transfer reactions, often coupled to proton transfer. The direct reaction of O 2 with fuel is precluded by the oxygen reduction reaction, which produces water and adenosine triphosphate. Cytochrome c oxidase affects the oxygen reduction reaction by binding O 2 in a heme ...
Generalized hypoxia is a medical condition in which the tissues of the body are deprived of the necessary levels of oxygen due to an insufficient supply of oxygen, which may be due to the composition or pressure of the breathing gas, decreased lung ventilation, or respiratory disease, any of which may cause a lower than normal oxygen content in the arterial blood, and consequently a reduced ...