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Leukocyte esterase (LE) is an esterase (a type of enzyme) produced by leukocytes (white blood cells). A leukocyte esterase test (LE test) is a urine test for the presence of white blood cells and other abnormalities associated with infection. White blood cells in the urine can indicate a urinary tract infection (UTI). Positive test results may ...
The false positive rate is calculated as the ratio between the number of negative events wrongly categorized as positive (false positives) and the total number of actual negative events (regardless of classification). The false positive rate (or "false alarm rate") usually refers to the expectancy of the false positive ratio.
In the setting of UTI symptoms, positive dipstick results for nitrite and leukocyte esterase are strongly suggestive of a UTI, [138] [139] but negative results do not rule it out if there is a high degree of suspicion.
The test for leukocyte esterase is indicative and does not replace microscopic examination of urine. [ 19 ] It is normal to find up to 3 (occasionally 5) leukocytes per high power field (40X) in a urine sample, with women having slightly higher results owing to vaginal contamination.
The false positive rate (FPR) is the proportion of all negatives that still yield positive test outcomes, i.e., the conditional probability of a positive test result given an event that was not present. The false positive rate is equal to the significance level. The specificity of the test is equal to 1 minus the false positive rate.
Measurement Lower limit Upper limit Unit Urinary specific gravity: 1.003 [1] [2]: 1.030 [1] [2]: g/mL Urobilinogen: 0.2 [2]: 1.0 [2]: Ehrlich units or mg/dL : Free catecholamines, dopamine ...
The false positive rate on rapid antigen testing is rare. One study from 2022 estimated that 0.05% of positive tests were false positives. Richard Watkins M.D., ...
False positive rate (FPR), Fall-out, probability of false alarm = Σ False positive / Σ Condition negative Positive likelihood ratio (LR+) = TPR / FPR Diagnostic odds ratio (DOR) = LR+ / LR− Matthews correlation coefficient (MCC) = √ TPR·TNR·PPV·NPV − √ FNR·FPR·FOR·FDR: F 1 score = 2 · PPV · TPR ...