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A related category of melanocytic proliferation is superficial atypical melanocytic proliferations of uncertain significance (SAMPUS). This category, unlike MELTUMP, which implies as yet undetermined potential for metastases even after complete excision, signifies lesions without metastatic potential at time of excision but with potential to ...
pathology; Dysplastic nevus: Usually a compound nevus with cellular and architectural dysplasia. Like typical moles, dysplastic nevi can be flat or raised. While they vary in size, dysplastic nevi are typically larger than normal moles and tend to have irregular borders and irregular coloration.
Download as PDF; Printable version ... Melanocytic tumors are tumors developed from melanocytes. [1] [2] Types. Melanocytic nevus; Melanocytic tumors of uncertain ...
However, a melanocytic nevus is benign, and melanoma is malignant. Most melanocytic nevi never evolve into a cancer, with the lifetime risk for an individual nevus being 1 in 3000 for men and 1 in 11 000 for women. [5] Moreover, dermatologists have a standardized system for determining whether a skin lesion is suspicious for malignant melanoma.
Although a nevus and a melanoma are often treated as independent entities, there is evidence that a nevus can be a precursor for a melanoma. [1] Common mutations have been identified in nevi and melanomas. [2] [3] [4]
Melanocytic nevi and neoplasms are caused by either a proliferation of (1) melanocytes, or (2) nevus cells, a form of melanocyte, but which lack dendritic processes. Contents Top
A melanocytoma is a rare pigmented tumor that has been described as a variant of the melanocytic nevus [1] and is derived from the neural crest. [2] The term "melanocytoma" was introduced by Limas and Tio in 1972.
Nevus cells are a variant of melanocytes. [1]: 684 They are larger than typical melanocytes, do not have dendrites, and have more abundant cytoplasm with coarse granules. [2] They are usually located at the dermoepidermal junction or in the dermis of the skin. Dermal nevus cells can be further classified: type A (epithelioid) dermal nevus cells ...