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Most cannabis drug tests yield a positive result when the concentration of THC-COOH in urine exceeds 50 ng/mL. [10] Urine testing is an immunoassay based test on the principle of competitive binding. Drugs which may be present in the urine specimen compete against their respective drug conjugate for binding sites on their specific antibody.
For instance, when the release of the inhibitory transmitter GABA is reduced, the net effect is an increase in the excitability of the endocannabinoid-releasing cell. On the converse, when release of the excitatory neurotransmitter glutamate is reduced, the net effect is a decrease in the excitability of the endocannabinoid-releasing cell.
There is a slight increase in dose proportionality in terms of peak and area-under-the-curve levels of THC with increasing oral doses over a range of 2.5 to 10 mg. [21] A high-fat meal delays time to peak concentrations of oral THC by 4 hours on average and increases area-under-the-curve exposure by 2.9-fold, but peak concentrations are not ...
(cell death) in non-cancerous cells than in melanoma cells.” The study is a notable addition to a growing body of work suggesting marijuana can do a lot more than get people high. However, there ...
A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Using marijuana daily for years may raise the overall risk of head and neck cancers three- to five-fold, according to a new study that analyzed millions of medical records. “Our research shows ...
Similar to one of the most enduring myths about LSD, and also somewhat related to the "multi-day impairment" legend described further down on this list, this legend claims that residual THC stored in fat cells gets released spontaneously into the bloodstream in enough quantities to get one high again long after the last use of cannabis, be it ...
Marijuana continues to be legalized across the U.S., with 22 states and Washington, D.C., allowing for the legal use and sale of the drug. With that, there seems to be a general consensus that ...