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Photodynamic therapy (PDT) is a form of phototherapy involving light and a photosensitizing chemical substance used in conjunction with molecular oxygen to elicit cell death (phototoxicity). [ 1 ] PDT is used in treating acne , wet age-related macular degeneration , psoriasis , and herpes .
The efficacy of antimicrobial photodynamic therapy, using various distinct photosensitizers, has been studied since the 1990s. [ 9 ] [ 7 ] Most studies have yielded positive outcomes, often achieving disinfection levels, as defined by infection control guidelines, exceeding 5 log 10 (99.999%) of microbial inactivation. [ 14 ]
Dental infections tend to also respond better to photothermal therapy than photodynamic therapy, though both have a strong effect. [ 10 ] [ 11 ] [ 12 ] The efficacy of PDT for antimicrobial usage is limited by the properties of the membrane of the target cell such as the electrical gradient ( membrane potential ) and lipid composition.
The International Joint Commission on Allied Health Personnel in Ophthalmology (IJCAHPO) is an American nonprofit professional association for Allied Ophthalmic Personnel (AOP). Founded in 1969, the IJCAHPO provides certification and education programs for persons in the ophthalmology field.
Light therapy, also called phototherapy or bright light therapy is the exposure to direct sunlight or artificial light at controlled wavelengths in order to treat a variety of medical disorders, including seasonal affective disorder (SAD), circadian rhythm sleep-wake disorders, cancers, neonatal jaundice, and skin wound infections.
Ophthalmology (/ˌɒfθælˈmɒlədʒi/ OFF-thal-MOL-ə-jee) is a surgical subspecialty within medicine that handles the diagnosis and treatment of eye disorders.[1] [2] Ophthalmologists are physicians (M.D./D.O/have a doctorate in medicine) that undergo subspecialty training in medical and surgical eye care. [3]